CGRRF1

Across TCGA pan-cancer cohorts, CGRRF1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CGRRF1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CGRRF1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CGRRF1 expression acts as an unfavorable survival marker.

LUAD and LSCC are the cancer types where CGRRF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.360	0.800	.038	12	view →
LSCC	DFS	Tertile	III,IV	0.322	0.888	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CGRRF1–LUAD (OS)

Open the LUAD breakdown →