Across TCGA patient cohorts, CGB8 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CGB8-associated genes across cancer lineages are MIR4734, MIR6085, and JADRR. Each is linked with CGB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGB8-to-partner and partner-to-CGB8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB8→partner) and Y-score (partner→CGB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4734 →	+0.389	+3.224	.004	.004	3	1
SKCM	MIR6085 →	+0.451	+3.875	<.001	.006	3	1
SKCM	JADRR →	+0.055	+3.801	<.001	.007	3	1
BLCA	RNU6-258P →	+0.328	+7.640	<.001	.009	3	1
SKCM	SPRYD7P1 →	+0.079	+4.282	<.001	.009	3	1
SKCM	VDAC2P4 →	+0.076	+3.661	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

CGB8 survival (RNA) · tumor vs normal (RNA) · all CGB8 data types