CGB2

Across TCGA patient cohorts, CGB2 protein abundance is significantly associated with the RNA expression of many other genes, with 266 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CGB2-associated genes across cancer lineages are CRYBB1, TJP1, and MINDY4. Each is linked with CGB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGB2-to-partner and partner-to-CGB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CGB2 versus CRYBB1 in LUAD, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB2→partner) and Y-score (partner→CGB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CRYBB1 →	+0.726	+1.196	.006	.008	3	1
LUAD	TJP1 →	-1.665	-1.519	.001	.009	3	1
LUAD	MINDY4 →	-0.773	-1.196	.001	.008	3	1
LUAD	EIF1B →	-0.623	-1.196	.005	.008	3	1
LUAD	TANC1 →	-1.303	-1.196	.002	.008	3	1
LUAD	MOB4 →	-1.010	-1.519	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 266 associations by consensus.

CGB2 vs CRYBB1 — LUAD

Explore this scatter interactively →