CGB2

Across TCGA pan-cancer cohorts, CGB2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CGB2 data layer compared with 4 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CGB2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CGB2 expression acts as an unfavorable survival marker.

LIHC, KIRC, and ACC are the cancer types where CGB2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.170	0.700	<.001	126	view →
KIRC	OS	Tertile	All	0.405	0.657	<.001	102	view →
ACC	OS	Tertile	III,IV	0.390	0.821	<.001	98	view →
THCA	DFS	Tertile	All	0.135	0.820	<.001	96	view →
STAD	DFS	Median	All	0.249	0.610	<.001	93	view →
MESO	OS	Tertile	II,III,IV	0.279	0.590	.003	54	view →
COAD	OS	Tertile	II,III,IV	0.559	0.797	.001	51	view →
SKCM	DFS	Tertile	III,IV	0.311	0.635	<.001	36	view →
BRCA	OS	Tertile	All	0.435	0.591	.016	18	view →
DLBC	DFS	Tertile	All	0.512	0.940	.007	18	view →
CHOL	OS	Tertile	All	0.185	0.755	.006	18	view →
LUAD	DFS	Tertile	IV	0.671	0.893	.019	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

CGB2–LIHC (OS)

Open the LIHC breakdown →