CGA

Across TCGA patient cohorts, CGA RNA expression is significantly associated with the go_rna of many other GO terms, with 6,794 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible CGA-associated GO terms across cancer lineages are ESCRT complex disassembly, Heart valve development, and Extracellular matrix assembly. Each is linked with CGA in more than 8 cancer types. Because this analysis shows association rather than direction, both CGA-to-partner and partner-to-CGA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ESCRT complex disassembly grouped by CGA-low versus CGA-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CGA→partner) and Y-score (partner→CGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ESCRT complex disassembly →	+0.070	+0.386	<.001	<.001	3	9
TGCT	Heart valve development →	+0.054	+1.853	<.001	<.001	3	9
TGCT	Extracellular matrix assembly →	+0.082	+1.932	<.001	<.001	3	8
ESCA	Regulation of endothelial cell migration →	+0.062	+0.478	<.001	.007	3	8
TGCT	Placenta development →	+0.030	+1.898	<.001	<.001	3	8
TGCT	Sprouting angiogenesis →	+0.029	+2.048	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,794 associations by consensus.

ESCRT complex disassembly by CGA expression — STAD

Explore this box plot interactively →