CFHR2

Across TCGA cell cohorts, CFHR2 RNA expression is significantly associated with the mutation status of many other genes, with 663 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CFHR2-associated genes across cancer lineages are THADA, PALM2AKAP2, and ARSJ. Each is linked with CFHR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CFHR2-to-partner and partner-to-CFHR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, THADA grouped by CFHR2-low versus CFHR2-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR2→partner) and Y-score (partner→CFHR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	THADA →	+3.342	+0.030	.008	<.001	3	3
BLOOD_Leukemia	PALM2AKAP2 →	+4.124	+0.174	<.001	<.001	3	3
BLOOD_Leukemia	ARSJ →	+4.539	+0.296	.007	<.001	3	3
LARGE_INTESTINE	TENT5A →	+5.022	+0.057	.002	<.001	3	3
BLOOD_Leukemia	RSPO3 →	+5.539	+0.395	.003	<.001	3	3
BLOOD_Leukemia	SCN4A →	+3.124	+0.111	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 663 associations by consensus.

THADA by CFHR2 expression — BLOOD_Lymphoma

Explore this box plot interactively →