CFAP46

Across TCGA patient cohorts, CFAP46 protein abundance is significantly associated with the RNA expression of many other genes, with 1,250 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CFAP46-associated genes across cancer lineages are HIGD1AP13, POFUT1, and E2F3. Each is linked with CFAP46 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP46-to-partner and partner-to-CFAP46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFAP46 versus HIGD1AP13 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP46→partner) and Y-score (partner→CFAP46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HIGD1AP13 →	+0.473	+0.759	<.001	.002	3	2
LUAD	POFUT1 →	+0.530	+0.266	.008	.001	3	1
LUAD	E2F3 →	+0.744	+0.371	.002	.008	3	1
LUAD	CCT4 →	+1.023	+0.371	<.001	.008	3	1
LUAD	OTX1 →	+1.170	+0.558	<.001	.007	3	1
LUAD	MRPS2 →	+0.796	+0.260	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,250 associations by consensus.

CFAP46 vs HIGD1AP13 — LSCC

Explore this scatter interactively →