CFAP410

Across TCGA patient cohorts, CFAP410 mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP410-associated genes across cancer lineages are POLDIP3, TTLL12, and FOXRED2. Each is linked with CFAP410 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP410-to-partner and partner-to-CFAP410 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POLDIP3 grouped by CFAP410-low versus CFAP410-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP410→partner) and Y-score (partner→CFAP410) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLDIP3 →	+0.614	+3.210	.004	.009	3	1
UCEC	TTLL12 →	+0.690	+3.332	.007	.005	3	1
UCEC	FOXRED2 →	+0.783	+3.354	.002	.005	3	1
UCEC	PHF5A →	+0.600	+3.226	.003	.009	3	1
UCEC	GNPNAT1 →	+0.741	+3.201	.009	.009	3	1
UCEC	DNAJA3 →	+0.544	+3.402	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

POLDIP3 by CFAP410 expression — UCEC

Explore this box plot interactively →