CFAP410

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CFAP410 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CFAP410’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CFAP410 RNA is repressed in tumor relative to normal tissue. In most cancer types CFAP410 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LUAD are the cancer types where CFAP410 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CFAP410 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHMaleAll−1.042<.00110view →
THCAMaleIII,IV−0.712<.0019view →
LUADMaleII,III,IV−0.773<.0018view →
KIRPMaleAll−0.553<.0017view →
UCECAllAll−0.678<.0016view →
CHOLAllAll+0.723.0014view →
LUSCMaleAll−0.573<.0014view →
BRCAAllII,III,IV−0.367<.0014view →
LIHCFemaleAll+0.505<.0013view →
ESCAAllII,III,IV+0.620.0412view →
KIRCMaleAll−0.290.0182view →
COADAllII,III,IV−0.207.0322view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CFAP410–KICH

Tumor-vs-normal expression box plot for CFAP410 RNA in KICH.

Open the KICH breakdown →

Exploration