CFAP410

Across TCGA pan-cancer cohorts, CFAP410 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CFAP410 data layer compared with 5 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher CFAP410 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CFAP410 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

PAAD, HNSC, and KIRP are the cancer types where CFAP410 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.552	0.249	<.001	53	view →
HNSC	DFS	Median	III,IV	0.427	0.250	.001	25	view →
KIRP	OS	Tertile	All	0.933	0.819	.010	24	view →
COAD	DFS	Quartile	II,III,IV	0.369	0.614	.007	21	view →
DLBC	DFS	Quartile	II,III,IV	1.000	0.114	.010	21	view →
CESC	DFS	Median	II,III,IV	0.325	0.598	.006	20	view →
READ	DFS	Quartile	IV	0.408	0.794	.012	17	view →
MESO	DFS	Tertile	All	0.652	0.189	.012	15	view →
STAD	DFS	Tertile	IV	0.168	0.670	.026	12	view →
BLCA	OS	Quartile	IV	0.205	0.658	.009	10	view →
UVM	OS	Median	All	0.433	0.822	.029	8	view →
LIHC	DFS	Quartile	III,IV	0.271	0.681	.012	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CFAP410–PAAD (OS)

Open the PAAD breakdown →