CFAP410

Across TCGA patient cohorts, CFAP410 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP410-associated genes across cancer lineages are A-Raf_pS299, NF2, and p62 Lck ligand. Each is linked with CFAP410 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP410-to-partner and partner-to-CFAP410 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by CFAP410-low versus CFAP410-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP410→partner) and Y-score (partner→CFAP410) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.224	-3.000	.001	.037	3	1
UCEC	NF2 →	+0.286	+3.000	.022	.037	3	1
UCEC	p62 Lck ligand →	+0.498	+3.009	.008	.019	3	1
UCEC	Annexin-1 →	+1.015	+2.827	<.001	.035	3	1
UCEC	Shc_pY317 →	-0.236	-3.000	.007	.036	3	1
UCEC	Caspase-7-cleavedD198 →	+0.704	+3.000	.040	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

A-Raf_pS299 by CFAP410 expression — UCEC

Explore this box plot interactively →