CFAP410

Across TCGA cell cohorts, CFAP410 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,928 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CFAP410-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Positive regulation of double-strand break repair, and Pre-mRNA catabolic process. Each is linked with CFAP410 in more than 13 cancer types. Because this analysis shows association rather than direction, both CFAP410-to-partner and partner-to-CFAP410 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by CFAP410-low versus CFAP410-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP410→partner) and Y-score (partner→CFAP410) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.108	+1.390	<.001	<.001	3	14
STOMACH	Positive regulation of double-strand break repair →	+0.075	+0.824	.007	.002	3	14
BONE	Pre-mRNA catabolic process →	+0.222	+0.939	<.001	.001	3	13
OESOPHAGUS	ATP metabolic process →	+0.101	+0.960	.003	.002	2	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.126	+0.784	.004	.008	2	14
OESOPHAGUS	Protein deacylation →	+0.112	+1.123	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,928 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by CFAP410 expression — BONE

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