CFAP410

Across TCGA cell cohorts, CFAP410 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP410-associated genes across cancer lineages are BHLHE23, SLC15A5, and SCT. Each is linked with CFAP410 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP410-to-partner and partner-to-CFAP410 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BHLHE23 grouped by CFAP410-low versus CFAP410-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP410→partner) and Y-score (partner→CFAP410) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	BHLHE23 →	+0.043	+5.357	<.001	.003	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	SCT →	+0.198	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

BHLHE23 by CFAP410 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →