Across TCGA cell cohorts, CFAP299 mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP299-associated genes across cancer lineages are PARD6A, SLC39A14, and DNASE2. Each is linked with CFAP299 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP299-to-partner and partner-to-CFAP299 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP299→partner) and Y-score (partner→CFAP299) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PARD6A →	+0.749	+3.299	.007	.004	3	1
LARGE_INTESTINE	SLC39A14 →	+0.779	+3.237	.006	.003	3	1
LARGE_INTESTINE	DNASE2 →	+0.944	+3.212	.002	.006	3	1
LARGE_INTESTINE	FAM149A →	+1.266	+3.212	.002	.006	3	1
LARGE_INTESTINE	CEP85L →	+0.642	+3.212	<.001	.006	3	1
LARGE_INTESTINE	ULBP1 →	+1.692	+3.257	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

Exploration

CFAP299 survival (RNA) · tumor vs normal (RNA) · all CFAP299 data types