CFAP299

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CFAP299 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CFAP299’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CFAP299 RNA is repressed in tumor relative to normal tissue. In most cancer types CFAP299 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and LUAD are the cancer types where CFAP299 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CFAP299 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAMaleIII,IV−0.391<.00111view →
LUSCAllII,III,IV−0.842<.0018view →
LUADAllII,III,IV−0.682<.0018view →
KIRCAllAll+0.086.0016view →
KICHFemaleII,III,IV−0.195<.0014view →
COADAllIV−0.012.0184view →
BLCAAllAll+0.125.0333view →
UCECAllAll−0.620.0442view →
KIRPFemaleII,III,IV−0.092.0412view →
LIHCFemaleAll+0.012.0342view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

Exploration