CES2

Across TCGA patient cohorts, CES2 mutation is significantly associated with the RNA expression of many other genes, with 1,773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CES2-associated genes across cancer lineages are TSEN15P3, RNA5SP24, and SPDYE9. Each is linked with CES2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CES2-to-partner and partner-to-CES2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSEN15P3 grouped by CES2-low versus CES2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CES2→partner) and Y-score (partner→CES2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	TSEN15P3 →	+0.094	+3.859	<.001	.003	3	3
LUSC	RNA5SP24 →	+1.425	+8.336	<.001	<.001	3	3
LUSC	SPDYE9 →	+0.029	+5.792	<.001	.003	3	3
LUAD	NIPA2P2 →	+0.053	+4.984	<.001	.005	3	3
LUAD	RN7SL423P →	+0.263	+5.629	.001	<.001	3	3
SKCM	MIR206 →	+0.135	+5.647	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,773 associations by consensus.

TSEN15P3 by CES2 expression — STAD

Explore this box plot interactively →