CERS4

Across TCGA patient cohorts, CERS4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,271 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CERS4-associated genes across cancer lineages are ITGA11, GPR161, and KIAA1755. Each is linked with CERS4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CERS4-to-partner and partner-to-CERS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CERS4 versus ITGA11 in OV, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS4→partner) and Y-score (partner→CERS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGA11 →	-0.958	-0.352	.004	.002	3	4
BRCA	GPR161 →	-0.981	-1.038	<.001	<.001	3	4
BRCA	KIAA1755 →	-0.802	-0.855	.003	<.001	3	4
HNSC	PLXDC1 →	-0.615	-0.372	<.001	.001	3	4
LSCC	ZNF454 →	-0.514	-0.473	.003	.001	3	4
OV	NTM →	-1.009	-0.315	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,271 associations by consensus.

CERS4 vs ITGA11 — OV

Explore this scatter interactively →