CERS4

Across TCGA cell cohorts, CERS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,999 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CERS4-associated GO terms across cancer lineages are Regulation of myoblast fusion, Purine ribonucleotide biosynthetic process, and tRNA aminoacylation for protein translation. Each is linked with CERS4 in more than 10 cancer types. Because this analysis shows association rather than direction, both CERS4-to-partner and partner-to-CERS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CERS4-low versus CERS4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CERS4→partner) and Y-score (partner→CERS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.112	+1.952	<.001	.003	3	11
BONE	Purine ribonucleotide biosynthetic process →	+0.102	+2.323	<.001	<.001	3	9
STOMACH	tRNA aminoacylation for protein translation →	+0.111	+3.151	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of signaling receptor activity →	-0.110	-1.027	.003	.003	3	9
OVARY	Negative regulation of myoblast fusion →	+0.108	+1.892	.001	.004	3	9
STOMACH	Cytoplasmic translation →	+0.103	+2.900	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,999 associations by consensus.

Regulation of myoblast fusion by CERS4 expression — OVARY

Explore this box plot interactively →