CEP85L

Across TCGA patient cohorts, CEP85L mutation is significantly associated with the RNA expression of many other genes, with 5,308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP85L-associated genes across cancer lineages are GNPNAT1, RNU6-1297P, and IL1R1-AS1. Each is linked with CEP85L in more than 3 cancer types. Because this analysis shows association rather than direction, both CEP85L-to-partner and partner-to-CEP85L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNPNAT1 grouped by CEP85L-low versus CEP85L-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP85L→partner) and Y-score (partner→CEP85L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GNPNAT1 →	+0.988	+3.478	<.001	.002	3	4
CESC	RNU6-1297P →	+0.560	+4.304	<.001	.003	3	3
CESC	IL1R1-AS1 →	+0.261	+4.166	<.001	.004	3	3
COAD	C1QBP →	+0.571	+2.235	.001	.006	3	3
COAD	MRM3 →	+0.452	+2.615	.001	.005	3	3
UCEC	TIMM22 →	+0.467	+3.597	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,308 associations by consensus.

GNPNAT1 by CEP85L expression — SKCM

Explore this box plot interactively →