CEP57L1

Across TCGA patient cohorts, CEP57L1 mutation is significantly associated with the RNA expression of many other genes, with 2,189 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP57L1-associated genes across cancer lineages are RN7SL248P, RNU6ATAC26P, and POMPP1. Each is linked with CEP57L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP57L1-to-partner and partner-to-CEP57L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CEP57L1-low versus CEP57L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP57L1→partner) and Y-score (partner→CEP57L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.077	+3.500	<.001	.002	3	2
SKCM	RNU6ATAC26P →	+0.285	+3.669	<.001	.006	3	2
UCEC	POMPP1 →	+0.114	+2.921	.001	.002	3	2
UCEC	LINC02071 →	+0.113	+2.444	<.001	<.001	3	2
SKCM	TAB3P1 →	+0.072	+4.290	<.001	<.001	3	2
LUAD	OR8F1P →	+0.140	+5.554	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,189 associations by consensus.

RN7SL248P by CEP57L1 expression — UCEC

Explore this box plot interactively →