CEP44

Across TCGA patient cohorts, CEP44 mutation is significantly associated with the RNA expression of many other genes, with 1,866 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP44-associated genes across cancer lineages are RNA5SP423, DCP1A, and ZNHIT3. Each is linked with CEP44 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP44-to-partner and partner-to-CEP44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP423 grouped by CEP44-low versus CEP44-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP44→partner) and Y-score (partner→CEP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP423 →	+0.541	+1.565	<.001	.008	3	3
UCEC	DCP1A →	+0.415	+1.652	.005	.006	3	2
UCEC	ZNHIT3 →	+0.460	+3.776	<.001	<.001	3	2
CESC	NUS1P4 →	+0.073	+5.010	<.001	.009	3	2
LGG	PRAMEF34P →	+0.029	+7.977	<.001	.007	3	2
BRCA	HMGB1P12 →	+0.075	+4.883	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,866 associations by consensus.

RNA5SP423 by CEP44 expression — UCEC

Explore this box plot interactively →