CEP44

Across TCGA pan-cancer cohorts, CEP44 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CEP44’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CEP44 RNA is repressed in tumor relative to normal tissue. In most cancer types CEP44 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA, LIHC, and CHOL are the cancer types where CEP44 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CEP44 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.446	<.001	8	view →
LIHC	Female	II,III,IV	+0.846	<.001	7	view →
CHOL	Female	All	+1.490	<.001	5	view →
HNSC	All	III,IV	+0.380	.011	3	view →
UCEC	All	All	−0.693	<.001	2	view →
LUAD	Female	II,III,IV	−0.326	.006	2	view →
BRCA	Female	All	−0.173	.028	2	view →
COAD	Male	All	+0.338	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CEP44–THCA

Open the THCA breakdown →