CEP41

Across TCGA patient cohorts, CEP41 mutation is significantly associated with the RNA expression of many other genes, with 2,423 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP41-associated genes across cancer lineages are SPATA31A3, VTRNA2-2P, and KIR3DP1. Each is linked with CEP41 in more than 2 cancer types. Because this analysis shows association rather than direction, both CEP41-to-partner and partner-to-CEP41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31A3 grouped by CEP41-low versus CEP41-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP41→partner) and Y-score (partner→CEP41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SPATA31A3 →	+0.014	+5.087	<.001	.004	3	3
UCEC	VTRNA2-2P →	+0.342	+1.895	.001	.007	3	3
BRCA	KIR3DP1 →	+0.044	+8.055	<.001	.007	3	2
UCEC	RN7SL248P →	+0.062	+3.219	<.001	.004	3	2
BRCA	RNU6-278P →	+0.232	+7.731	<.001	.009	3	2
LUSC	RNA5SP432 →	+0.379	+5.978	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,423 associations by consensus.

SPATA31A3 by CEP41 expression — LUAD

Explore this box plot interactively →