CEP41

Across TCGA pan-cancer cohorts, CEP41 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CEP41 data layer compared with 6 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher CEP41 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CEP41 expression acts as an unfavorable survival marker, although some lineages such as READ and UCEC show a favorable association.

STAD, KICH, and LIHC are the cancer types where CEP41 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.196	0.632	<.001	62	view →
KICH	OS	Tertile	All	0.707	1.000	.003	59	view →
LIHC	OS	Tertile	All	0.562	0.770	<.001	52	view →
HNSC	OS	Tertile	All	0.444	0.805	<.001	45	view →
READ	OS	Median	III,IV	1.000	0.416	.001	41	view →
ACC	DFS	Tertile	All	0.427	0.777	.004	41	view →
KIRC	DFS	Tertile	IV	0.159	0.471	.003	36	view →
UCEC	OS	Quartile	III,IV	0.922	0.761	.005	34	view →
THYM	DFS	Quartile	All	0.969	0.785	.005	34	view →
COAD	OS	Tertile	All	0.818	0.506	.001	33	view →
MESO	DFS	Median	All	0.239	0.608	.005	30	view →
CESC	DFS	Median	All	0.777	0.865	.004	26	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CEP41–STAD (DFS)

Open the STAD breakdown →