CEP295

Across TCGA patient cohorts, CEP295 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,454 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CEP295-associated proteins across cancer lineages are SMC4, FAM76B_S193, and PRC1_T481. Each is linked with CEP295 in more than 6 cancer types. Because this analysis shows association rather than direction, both CEP295-to-partner and partner-to-CEP295 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CEP295 versus SMC4 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP295→partner) and Y-score (partner→CEP295) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC4 →	+0.603	+0.330	.002	.006	3	7
PDAC	FAM76B_S193 →	+0.597	+0.267	<.001	.007	3	7
CCRCC	PRC1_T481 →	+1.043	+0.314	.003	.009	3	6
GBM	SPC24 →	+0.484	+0.236	<.001	<.001	3	6
LSCC	SSRP1 →	+0.483	+0.510	<.001	.001	3	6
GBM	BUB3 →	+0.302	+0.356	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,454 associations by consensus.

CEP295 vs SMC4 — GBM

Explore this scatter interactively →