CEP19

Across TCGA patient cohorts, CEP19 mutation is significantly associated with the RNA expression of many other genes, with 858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CEP19-associated genes across cancer lineages are RNA5SP419, SNORD91B, and LINC02227. Each is linked with CEP19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP19-to-partner and partner-to-CEP19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by CEP19-low versus CEP19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP19→partner) and Y-score (partner→CEP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+1.037	+2.813	<.001	.003	3	2
UCEC	SNORD91B →	+0.550	+3.354	<.001	.005	3	1
UCEC	LINC02227 →	+0.136	+3.461	.007	.004	3	1
BLCA	RNU6-376P →	+0.455	+5.899	<.001	.002	3	1
UCEC	MIR6803 →	+0.251	+5.308	<.001	.001	3	1
BLCA	KIRREL3-AS2 →	+0.215	+5.106	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

RNA5SP419 by CEP19 expression — UCEC

Explore this box plot interactively →