CEP126

Across TCGA cell cohorts, CEP126 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CEP126-associated genes across cancer lineages are C7orf33, VN1R2, and SSX7. Each is linked with CEP126 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP126-to-partner and partner-to-CEP126 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C7orf33 grouped by CEP126-low versus CEP126-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP126→partner) and Y-score (partner→CEP126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	C7orf33 →	+0.435	+4.584	<.001	.001	3	1
LUNG_NSCLC_LUAD	VN1R2 →	+0.046	+4.544	<.001	.003	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
BLOOD_Lymphoma	AVP →	+0.038	+5.209	<.001	.005	3	1
BREAST	TAAR1 →	+0.041	+4.199	<.001	.007	3	1
BREAST	OR10K2 →	+0.047	+4.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C7orf33 by CEP126 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →