CENPU

Across TCGA patient cohorts, CENPU protein abundance is significantly associated with the RNA expression of many other genes, with 8,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPU-associated genes across cancer lineages are CDC20, CDCA8, and IQGAP3. Each is linked with CENPU in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPU-to-partner and partner-to-CENPU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPU versus CDC20 in LUAD, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPU→partner) and Y-score (partner→CENPU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDC20 →	+1.745	+0.476	.002	.001	3	7
LUAD	CDCA8 →	+1.487	+0.602	.002	.005	3	6
LUAD	IQGAP3 →	+2.184	+0.669	.002	.001	3	6
BRCA	KIF20A →	+1.448	+0.712	<.001	<.001	3	5
UCEC	NCAPH →	+1.111	+0.647	<.001	<.001	3	5
GBM	ASPM →	+1.331	+0.783	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,938 associations by consensus.

CENPU vs CDC20 — LUAD

Explore this scatter interactively →