CENPU

Across TCGA pan-cancer cohorts, CENPU RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of CENPU’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CENPU RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CENPU is over-expressed in tumor.

BLCA, KIRC, and KIRP are the cancer types where CENPU tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CENPU RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	IV	+2.701	<.001	12	view →
KIRC	All	IV	+1.609	<.001	12	view →
KIRP	All	IV	+2.622	<.001	11	view →
LUAD	Male	II,III,IV	+2.133	<.001	11	view →
THCA	Male	III,IV	+1.130	<.001	11	view →
LUSC	Female	II,III,IV	+3.557	<.001	9	view →
KICH	All	All	+1.075	<.001	9	view →
COAD	All	II,III,IV	+0.993	<.001	9	view →
LIHC	Male	All	+2.044	<.001	8	view →
STAD	All	All	+1.915	<.001	8	view →
HNSC	Male	All	+1.282	<.001	8	view →
UCEC	All	III,IV	+3.331	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

CENPU–BLCA

Open the BLCA breakdown →