CENPU

Across TCGA cell cohorts, CENPU RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPU-associated GO terms across cancer lineages are Nuclear division, Replication fork processing, and DNA-templated DNA replication maintenance of fidelity. Each is linked with CENPU in more than 18 cancer types. Because this analysis shows association rather than direction, both CENPU-to-partner and partner-to-CENPU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear division grouped by CENPU-low versus CENPU-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPU→partner) and Y-score (partner→CENPU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Nuclear division →	+0.095	+1.509	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Replication fork processing →	+0.126	+1.762	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.119	+1.655	<.001	<.001	3	19
LUNG_SCLC	Centrosome duplication →	+0.112	+1.319	<.001	<.001	3	19
SOFT_TISSUE	Meiotic cell cycle →	+0.084	+1.472	<.001	<.001	3	19
PANCREAS	DNA-templated DNA replication →	+0.143	+1.448	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Nuclear division by CENPU expression — SOFT_TISSUE

Explore this box plot interactively →