CENPT

Across TCGA cell cohorts, CENPT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,954 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CENPT-associated GO terms across cancer lineages are Microtubule nucleation, Microtubule polymerization, and Nucleic acid transport. Each is linked with CENPT in more than 14 cancer types. Because this analysis shows association rather than direction, both CENPT-to-partner and partner-to-CENPT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by CENPT-low versus CENPT-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPT→partner) and Y-score (partner→CENPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule nucleation →	+0.136	+1.238	<.001	<.001	3	15
LARGE_INTESTINE	Microtubule polymerization →	+0.128	+0.996	<.001	<.001	3	15
BONE	Nucleic acid transport →	+0.091	+0.695	<.001	.001	3	14
BONE	RNA transport →	+0.091	+0.695	<.001	.001	3	14
SOFT_TISSUE	mRNA transport →	+0.085	+0.676	<.001	.003	3	14
SOFT_TISSUE	Positive regulation of DNA metabolic process →	+0.060	+0.886	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,954 associations by consensus.

Microtubule nucleation by CENPT expression — LARGE_INTESTINE

Explore this box plot interactively →