CENPL

Across TCGA patient cohorts, CENPL protein abundance is significantly associated with the protein abundance of many other proteins, with 13,908 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CENPL-associated proteins across cancer lineages are CDC20_T70, SMC4, and TOP2A_S1106. Each is linked with CENPL in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPL-to-partner and partner-to-CENPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPL versus CDC20_T70 in LUAD, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPL→partner) and Y-score (partner→CENPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDC20_T70 →	+1.579	+0.677	<.001	<.001	3	7
LUAD	SMC4 →	+0.737	+0.718	<.001	<.001	3	7
LUAD	TOP2A_S1106 →	+1.383	+0.574	<.001	<.001	3	7
LUAD	MCM3 →	+0.982	+0.681	<.001	<.001	3	7
LUAD	NCAPG →	+0.747	+0.608	<.001	<.001	3	7
LUAD	NCAPH →	+0.730	+0.647	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,908 associations by consensus.

CENPL vs CDC20_T70 — LUAD

Explore this scatter interactively →