CENPC

Across TCGA patient cohorts, CENPC RNA expression is significantly associated with the protein abundance of many other proteins, with 18,468 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CENPC-associated proteins across cancer lineages are RANBP3, RPL7, and LMNB2. Each is linked with CENPC in more than 6 cancer types. Because this analysis shows association rather than direction, both CENPC-to-partner and partner-to-CENPC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPC versus RANBP3 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPC→partner) and Y-score (partner→CENPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RANBP3 →	+0.303	+0.522	.001	<.001	3	7
GBM	RPL7 →	-0.329	-0.275	<.001	<.001	3	6
PDAC	LMNB2 →	+0.347	+0.309	<.001	<.001	3	6
COAD	ZNF24 →	+0.368	+0.309	<.001	.001	3	5
GBM	RAD21 →	+0.245	+0.278	.002	.003	3	5
HNSC	XRCC1 →	+0.297	+0.757	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,468 associations by consensus.

CENPC vs RANBP3 — BRCA

Explore this scatter interactively →