CENPC

Across TCGA patient cohorts, CENPC protein abundance is significantly associated with the RNA expression of many other genes, with 4,604 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CENPC-associated genes across cancer lineages are FRMD4B, WLS, and WDFY2. Each is linked with CENPC in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPC-to-partner and partner-to-CENPC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CENPC versus FRMD4B in BRCA, with a Pearson correlation of -0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPC→partner) and Y-score (partner→CENPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FRMD4B →	-0.566	-0.258	.001	<.001	3	3
BRCA	WLS →	-1.149	-0.238	.002	.009	3	3
BRCA	WDFY2 →	-0.545	-0.281	<.001	<.001	3	3
BRCA	RBMS3 →	-0.514	-0.227	<.001	<.001	3	3
CCRCC	TMEM130 →	-1.420	-0.170	<.001	<.001	3	3
BRCA	KIRREL1 →	-0.892	-0.256	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,604 associations by consensus.

CENPC vs FRMD4B — BRCA

Explore this scatter interactively →