CENPB

Across TCGA cell cohorts, CENPB mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CENPB-associated genes across cancer lineages are OR10A5, PROP1, and CCT8L2. Each is linked with CENPB in more than 1 cancer types. Because this analysis shows association rather than direction, both CENPB-to-partner and partner-to-CENPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A5 grouped by CENPB-low versus CENPB-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPB→partner) and Y-score (partner→CENPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR10A5 →	+0.030	+4.906	<.001	.006	3	1
BLOOD_Leukemia	PROP1 →	+0.022	+4.289	<.001	<.001	3	1
BLOOD_Leukemia	CCT8L2 →	+0.007	+3.289	.001	.009	3	1
BLOOD_Leukemia	SERPINB11 →	+0.018	+3.289	<.001	.009	3	1
BLOOD_Leukemia	SERPINB3 →	+0.578	+3.819	<.001	.007	3	1
OVARY	OR7D4 →	+0.056	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

OR10A5 by CENPB expression — OESOPHAGUS

Explore this box plot interactively →