CEBPE

Across TCGA cell cohorts, CEBPE RNA expression is significantly associated with the go_rna of many other GO terms, with 1,159 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CEBPE-associated GO terms across cancer lineages are Isoleucine transport, Positive regulation of retrograde protein transport, ER to cytosol, and Leukotriene signaling pathway. Each is linked with CEBPE in more than 3 cancer types. Because this analysis shows association rather than direction, both CEBPE-to-partner and partner-to-CEBPE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Isoleucine transport grouped by CEBPE-low versus CEBPE-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CEBPE→partner) and Y-score (partner→CEBPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Isoleucine transport →	+0.127	+1.904	.001	<.001	3	4
BLOOD_Leukemia	Positive regulation of retrograde protein transport, ER to cytosol →	+0.073	+1.378	<.001	<.001	3	4
CNS	Leukotriene signaling pathway →	+0.718	+0.025	.006	.001	2	4
BREAST	Response to platelet-derived growth factor →	+0.075	+0.012	.007	.002	3	3
BLOOD_Myeloma	Negative regulation of activated T cell proliferation →	+0.179	+0.027	.002	.003	2	4
SKIN	Interleukin-10-mediated signaling pathway →	-0.115	-0.031	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,159 associations by consensus.

Isoleucine transport by CEBPE expression — BLOOD_Leukemia

Explore this box plot interactively →