CEBPE

Across TCGA pan-cancer cohorts, CEBPE RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CEBPE data layer compared with 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CEBPE RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CEBPE expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

HNSC, CESC, and STAD are the cancer types where CEBPE RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.426	0.238	<.001	126	view →
CESC	DFS	Median	II,III,IV	0.872	0.676	.002	54	view →
STAD	DFS	Median	All	0.586	0.816	.001	25	view →
UCS	OS	Median	II,III,IV	0.405	0.751	.002	22	view →
ESCA	OS	Quartile	All	0.650	0.411	.021	18	view →
LAML	DFS	Tertile	All	0.710	0.465	.022	16	view →
ACC	DFS	Tertile	All	0.760	0.329	.010	15	view →
SARC	OS	Tertile	All	0.830	0.636	.020	15	view →
UVM	DFS	Quartile	All	0.574	0.897	.012	13	view →
LUSC	DFS	Quartile	III,IV	0.732	0.198	.004	11	view →
LGG	DFS	Quartile	All	0.326	0.504	.001	11	view →
DLBC	OS	Quartile	All	0.576	1.000	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CEBPE–HNSC (DFS)

Open the HNSC breakdown →