Across TCGA patient cohorts, CDRT15 mutation is significantly associated with the RNA expression of many other genes, with 687 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDRT15-associated genes across cancer lineages are URGCP-MRPS24, HSPE1-MOB4, and CCL3. Each is linked with CDRT15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDRT15-to-partner and partner-to-CDRT15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDRT15→partner) and Y-score (partner→CDRT15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	URGCP-MRPS24 →	+0.230	+3.836	<.001	.001	3	1
UCEC	HSPE1-MOB4 →	+0.215	+3.384	<.001	<.001	3	1
UCEC	CCL3 →	+1.359	+3.354	<.001	.005	3	1
UCEC	PRSS53 →	+0.372	+3.254	.001	.008	3	1
UCEC	C16orf87 →	+0.654	+3.364	.002	.005	3	1
UCEC	MIER3 →	+0.675	+3.332	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 687 associations by consensus.

Exploration

CDRT15 survival (RNA) · tumor vs normal (RNA) · all CDRT15 data types