Across TCGA patient cohorts, CDRT15 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDRT15-associated genes across cancer lineages are JNK_pT183_Y185, Notch1, and TFRC. Each is linked with CDRT15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDRT15-to-partner and partner-to-CDRT15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDRT15→partner) and Y-score (partner→CDRT15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.235	-3.156	.011	.020	3	1
UCEC	Notch1 →	+0.318	+3.013	<.001	.018	3	1
UCEC	TFRC →	+0.586	+3.169	.044	.020	2	2
UCEC	VHL →	-0.990	-3.000	.007	.036	3	1
UCEC	Caspase-7-cleavedD198 →	+1.048	+3.169	.001	.020	1	2
UCEC	EGFR_pY1068 →	-0.342	-3.169	.013	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

CDRT15 survival (RNA) · tumor vs normal (RNA) · all CDRT15 data types