CDO1

Across TCGA cell cohorts, CDO1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CDO1-associated genes across cancer lineages are OR5B2, SCN10A, and OR8B4. Each is linked with CDO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDO1-to-partner and partner-to-CDO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5B2 grouped by CDO1-low versus CDO1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDO1→partner) and Y-score (partner→CDO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR5B2 →	+0.017	+3.684	<.001	.006	3	1
LUNG_NSCLC_LUAD	SCN10A →	+0.006	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.034	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR5B2 by CDO1 expression — LARGE_INTESTINE

Explore this box plot interactively →