CDO1

Across TCGA pan-cancer cohorts, CDO1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated CDO1 data layer compared with 4 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CDO1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CDO1 expression acts as an unfavorable survival marker, although some lineages such as UVM and LIHC show a favorable association.

UVM, LIHC, and LUAD are the cancer types where CDO1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.762	0.366	.002	66	view →
LIHC	OS	Median	All	0.819	0.587	<.001	65	view →
LUAD	OS	Median	II,III,IV	0.831	0.658	.007	46	view →
HNSC	DFS	Tertile	IV	0.477	0.336	.007	33	view →
SKCM	OS	Quartile	II,III,IV	0.590	0.218	.004	33	view →
BRCA	OS	Quartile	IV	0.934	0.323	.006	27	view →
STAD	OS	Tertile	All	0.536	0.669	.012	19	view →
SCLC	OS	Tertile	II,III,IV	0.659	0.284	.004	18	view →
PAAD	DFS	Tertile	All	0.429	0.212	.004	17	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	12	view →
READ	DFS	Median	III,IV	0.317	0.747	.008	11	view →
BLCA	OS	Quartile	III,IV	0.308	0.562	.024	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

CDO1–UVM (OS)

Open the UVM breakdown →