Across TCGA patient cohorts, CDNF mutation is significantly associated with the RNA expression of many other genes, with 153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDNF-associated genes across cancer lineages are RPL31P16, ANAPC1P5, and RPL21P129. Each is linked with CDNF in more than 1 cancer types. Because this analysis shows association rather than direction, both CDNF-to-partner and partner-to-CDNF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDNF→partner) and Y-score (partner→CDNF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPL31P16 →	+0.148	+3.518	.005	.005	3	2
HNSC	ANAPC1P5 →	+0.058	+3.517	<.001	.008	3	2
UCEC	RPL21P129 →	+0.249	+2.767	.001	.003	3	2
HNSC	RNU6-832P →	+0.181	+4.936	<.001	.003	3	1
HNSC	RNA5SP88 →	+0.239	+4.468	<.001	.006	3	1
HNSC	MIR153-2 →	+0.217	+5.357	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 153 associations by consensus.

Exploration

CDNF survival (RNA) · tumor vs normal (RNA) · all CDNF data types