CDKN2AIPNL

Across TCGA patient cohorts, CDKN2AIPNL mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDKN2AIPNL-associated genes across cancer lineages are FAM27B, LILRP1, and RN7SKP214. Each is linked with CDKN2AIPNL in more than 1 cancer types. Because this analysis shows association rather than direction, both CDKN2AIPNL-to-partner and partner-to-CDKN2AIPNL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM27B grouped by CDKN2AIPNL-low versus CDKN2AIPNL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDKN2AIPNL→partner) and Y-score (partner→CDKN2AIPNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM27B →	+0.131	+4.453	<.001	.006	3	2
UCEC	LILRP1 →	+0.205	+3.718	<.001	.006	3	1
UCEC	RN7SKP214 →	+0.323	+3.334	.003	.008	3	1
UCEC	RNU6-206P →	+0.372	+5.245	<.001	.002	3	1
UCEC	RNU6-906P →	+0.623	+3.671	<.001	.003	3	1
UCEC	TRGV9 →	+0.140	+3.641	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

FAM27B by CDKN2AIPNL expression — UCEC

Explore this box plot interactively →