CDK6-AS1

Across TCGA patient cohorts, CDK6-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,159 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible CDK6-AS1-associated GO terms across cancer lineages are Dedifferentiation, Positive regulation of fibroblast proliferation, and Fused antrum stage. Each is linked with CDK6-AS1 in more than 20 cancer types. Because this analysis shows association rather than direction, both CDK6-AS1-to-partner and partner-to-CDK6-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dedifferentiation grouped by CDK6-AS1-low versus CDK6-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK6-AS1→partner) and Y-score (partner→CDK6-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Dedifferentiation →	+0.096	+0.526	<.001	<.001	3	21
TGCT	Positive regulation of fibroblast proliferation →	+0.066	+1.359	<.001	<.001	3	16
TGCT	Fused antrum stage →	+0.090	+1.061	<.001	<.001	3	16
TGCT	Negative regulation of cellular senescence →	+0.068	+1.168	<.001	<.001	3	16
TGCT	Peptidyl-lysine oxidation →	+0.110	+0.976	<.001	<.001	3	15
TGCT	Lateral ventricle development →	+0.073	+1.349	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,159 associations by consensus.

Dedifferentiation by CDK6-AS1 expression — ESCA

Explore this box plot interactively →