CDK5R2

Across TCGA patient cohorts, CDK5R2 mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDK5R2-associated genes across cancer lineages are RNU6-805P, GYG2P1, and RNA5SP210. Each is linked with CDK5R2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK5R2-to-partner and partner-to-CDK5R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-805P grouped by CDK5R2-low versus CDK5R2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5R2→partner) and Y-score (partner→CDK5R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-805P →	+0.390	+4.934	<.001	.002	3	2
CESC	GYG2P1 →	+0.022	+4.601	.003	.004	3	2
COAD	RNA5SP210 →	+0.514	+4.537	<.001	.006	3	2
LUSC	RN7SKP65 →	+0.169	+5.706	<.001	.003	3	2
COAD	MIR4265 →	+0.718	+4.537	<.001	.006	3	2
LUSC	SAPCD2P2 →	+0.045	+5.038	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

RNU6-805P by CDK5R2 expression — CESC

Explore this box plot interactively →