CDK2AP1

Across TCGA patient cohorts, CDK2AP1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK2AP1-associated genes across cancer lineages are GMPS, PCDH19, and NT5DC2. Each is linked with CDK2AP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDK2AP1-to-partner and partner-to-CDK2AP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK2AP1 versus GMPS in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK2AP1→partner) and Y-score (partner→CDK2AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPS →	+0.721	+0.336	<.001	<.001	3	5
HNSC	PCDH19 →	+1.105	+0.278	.005	.008	3	5
HNSC	NT5DC2 →	+0.843	+0.350	<.001	.001	3	5
LSCC	CCDC34 →	+0.693	+0.361	<.001	<.001	3	4
LSCC	TIMM8A →	+0.433	+0.306	<.001	<.001	3	4
BRCA	SYTL2 →	-1.098	-0.315	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,284 associations by consensus.

CDK2AP1 vs GMPS — LSCC

Explore this scatter interactively →