CDK2AP1

Across TCGA patient cohorts, CDK2AP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 27,506 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDK2AP1-associated proteins across cancer lineages are KHDRBS1, ADNP, and RSRC2. Each is linked with CDK2AP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDK2AP1-to-partner and partner-to-CDK2AP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK2AP1 versus KHDRBS1 in GBM, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK2AP1→partner) and Y-score (partner→CDK2AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KHDRBS1 →	+0.265	+0.427	<.001	<.001	3	7
GBM	ADNP →	+0.448	+0.496	<.001	<.001	3	6
LSCC	RSRC2 →	+0.354	+0.448	<.001	<.001	3	6
GBM	SAMD1 →	+0.414	+0.330	<.001	<.001	3	6
GBM	GATAD2B →	+0.413	+0.480	<.001	<.001	3	6
GBM	HCFC1 →	+0.262	+0.464	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,506 associations by consensus.

CDK2AP1 vs KHDRBS1 — GBM

Explore this scatter interactively →