CDK2AP1

Across TCGA patient cohorts, CDK2AP1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDK2AP1-associated genes across cancer lineages are RNU6-170P, TAS2R7, and MIR7845. Each is linked with CDK2AP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK2AP1-to-partner and partner-to-CDK2AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-170P grouped by CDK2AP1-low versus CDK2AP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK2AP1→partner) and Y-score (partner→CDK2AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-170P →	+0.264	+4.292	<.001	.006	3	2
SKCM	TAS2R7 →	+0.041	+4.680	<.001	.007	3	1
UCEC	MIR7845 →	+0.724	+2.838	<.001	.009	3	1
UCEC	CCL1 →	+0.323	+3.058	<.001	.005	3	1
UCEC	IL21 →	+0.151	+2.763	.009	.009	3	1
UCEC	RNU6-629P →	+0.262	+4.137	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

RNU6-170P by CDK2AP1 expression — UCEC

Explore this box plot interactively →