CDK2AP1

Across TCGA patient cohorts, CDK2AP1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDK2AP1-associated genes across cancer lineages are Tuberin and YB-1. Each is linked with CDK2AP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK2AP1-to-partner and partner-to-CDK2AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin grouped by CDK2AP1-low versus CDK2AP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK2AP1→partner) and Y-score (partner→CDK2AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin →	+0.335	+2.817	.042	.036	3	1
UCEC	YB-1 →	+0.227	+2.833	.019	.035	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Tuberin by CDK2AP1 expression — UCEC

Explore this box plot interactively →