CDK2AP1

Across TCGA cell cohorts, CDK2AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,418 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDK2AP1-associated GO terms across cancer lineages are CMP biosynthetic process, Negative regulation of cell cycle process, and Regulation of microtubule-based process. Each is linked with CDK2AP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDK2AP1-to-partner and partner-to-CDK2AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP biosynthetic process grouped by CDK2AP1-low versus CDK2AP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK2AP1→partner) and Y-score (partner→CDK2AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	CMP biosynthetic process →	+0.094	+0.811	<.001	<.001	3	10
OVARY	Negative regulation of cell cycle process →	+0.060	+0.906	<.001	<.001	3	9
BLOOD_Leukemia	Regulation of microtubule-based process →	+0.037	+0.978	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of sister chromatid segregation →	+0.071	+0.820	.002	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA replication checkpoint signaling →	+0.085	+0.585	.009	.005	3	9
OVARY	Zinc ion import into lysosome →	-0.160	-0.745	.004	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,418 associations by consensus.

CMP biosynthetic process by CDK2AP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →